From molecules to networks: The dendritic processes that shape learning and memory

Organizers

Björn Kampa | RWTH Aachen University, Germany
Gaia Tavosanis | RWTH Aachen University, Germany
Willem Wybo | Forschungszentrum Jülich, Germany

Abstract

Neurons collect their synaptic input on large dendritic trees wherein these inputs are also integrated and processed. These mechanisms have been described already for several decades and brought forward many promising computational advantages. Yet, it has been the recent advance in optophysiological techniques that enables to measure dendritic activity in the intact brain of animals performing complex behavior tasks. New activity sensors, genetically engineered and tailored to report local dendritic signals opened new vistas and offer promising new research directions. At the same time, incorporating dendrites into deep neural networks has shown to improve their performance, reduce their energy requirements and allow learning continuously new content without forgetting previously acquired knowledge. The workshop brings together leading young and senior experts from the field covering experimental and computational work from the molecular to the systems level leading to new fundamental models and AI networks. The aim of the workshop is to exchange recently gained knowledge in a series of talks and to create new ideas in intense discussions.

Schedule (CEST)

Monday, Sept 29

14:00

Thomas Oertner | Center for Molecular Neurobiology Hamburg, Germany
Clustered postsynaptic density dynamics in CA1 hippocampal neurons

14:30

Corette Wierenga | Radboud University, Nijmegen, The Netherlands
Coordination of excitatory and inhibitory synapses via dendritic endocannabinoid signaling

15:00

Willem Wybo | Forschungszentrum Jülich, Germany
Dendritic modulation balances stability and plasticity

15:30

Discussion

16:00

Coffee break

16:30

Pier Stanislao Paolucci | Istituto Nazionale di Fisica Nucleare (INFN), Rome, Italy
Apical mechanism supporting incremental learning and sleep cycles

17:00

Tobias Bock | RWTH Aachen University, Germany
The impact of synapse distribution on synchronous signal propagation in pyramidal neurons

17:30

Hermann Cuntz | Ernst Strüngmann Institute (ESI) for Neuroscience, Frankfurt am Main, Germany
Dendritic diameters and neural computation 

18:00

Discussion

Tuesday, Sept 30

8:30

Yiota Poirazi | Foundation of Research and Technology-Hellas (FORTH), Greece
Clustered spine dynamics in M2 pyramidal neurons during flexible behavior

9:00

Albert Gidon | Humboldt University Berlin, Germany
Dendritic spikes as a widespread mode of operation in the cortex

9:30

Marlene Bartos | University of Freiburg, Germany
Dendrite-targeting interneurons provide predictive coding of goal sites in the dentate gyrus of behaving mice

10:00

Discussion

10:30

Coffee break

11:00

Walter Senn | University of Bern, Switzerland
Dendritic computation, attention, and cognition

11:30

Viola Priesemann | Max Planck Institute for Dynamics and Self-Organization, Göttingen, Germany
Dendritic balance and error computation

12:00

Julijana Gjorgjieva | Technical University Munich, Germany
Assembly-based computations through dendritic contextual gating of plasticity

12:30

Discussion